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VOLULIP
Lips in volume
Sederma has now developed VOLULIP
an active substance containing a plant Portulaca "Kiss-me-quick"
extract, associated with a natural modified matrikine-mimetic peptide,
whose main activity is to stimulate hyaluronic
acid synthesis.
In order to demonstrate the product efficacy and its mechanism of
action, several in vitro tests have been carried out following
3 axes, stimulation of dermal matrix molecules (collagen 1, collagen
3, fibronectin, HSP47), reinforcement of DEJ molecules (collagen
4, laminin 5), improvement of hydric sphere (hyaluronic acid, aquaporin
3).
Sederma also carried out 2 clinical studies to prove VOLULIP
efficacy on youth, hydration and lip volume.
The first one involved 29 panellists with a twice daily application
of a balm containing 1% VOLULIP
for a month. It associated several complementary methods such
as Aeroflexmeter® (device developed and patented by Sederma
which allows to characterise skin mechanical properties without
any contact, thanks to a compressed air jet), fringe projections
(FOITS) and MoistureMeter-D.
The second one was carried out on a total of 21 panellists to
measure re-densification with an ultrasonor echograph.
The results are very significant. We observed a gain of +13.3%
of firmness, +50.6% of hydration, +10.5% of softness, +15.1% of
volume, +9.2% of curvature (radius of curvature of the
lower lip) and an increase of +19.6% of the surface of the central
area of the lower lip for volunteers with very fine lips.
To find out more about VOLULIP,
don't hesitate to contact
us!
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