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Volulip

VOLULIP™

Lips in volume

Sederma has now developed VOLULIP™ an active substance containing a plant Portulaca "Kiss-me-quick" extract, associated with a natural modified matrikine-mimetic peptide, whose main activity is to stimulate hyaluronic acid synthesis.
In order to demonstrate the product efficacy and its mechanism of action, several in vitro tests have been carried out following 3 axes, stimulation of dermal matrix molecules (collagen 1, collagen 3, fibronectin, HSP47), reinforcement of DEJ molecules (collagen 4, laminin 5), improvement of hydric sphere (hyaluronic acid, aquaporin 3).

Sederma also carried out 2 clinical studies to prove VOLULIP™ efficacy on youth, hydration and lip volume.
The first one involved 29 panellists with a twice daily application of a balm containing 1% VOLULIP™ for a month. It associated several complementary methods such as Aeroflexmeter® (device developed and patented by Sederma which allows to characterise skin mechanical properties without any contact, thanks to a compressed air jet), fringe projections (FOITS) and MoistureMeter-D.
The second one was carried out on a total of 21 panellists to measure re-densification with an ultrasonor echograph.

The results are very significant. We observed a gain of +13.3% of firmness, +50.6% of hydration, +10.5% of softness, +15.1% of volume, +9.2% of curvature (radius of curvature of the lower lip) and an increase of +19.6% of the surface of the central area of the lower lip for volunteers with very fine lips.


To find out more about VOLULIP™, don't hesitate to contact us!